Our research interests mainly include three directions: 1) neurobiomimetic materials; 2) Brain like computing devices; 3) Neuroregulatory techniques. Research directions include but are not limited to: micro/nano fluids, hydrogels, porous membranes, flexible wearable devices, bioelectronic interfaces, neural morphology computing, neuroelectrophysiological regulation and other interdisciplinary fields.
At present, the specific research directions are as follows:
1. Biomimetic ion based intelligent sensing and energy devices
Biointelligent sensing (such as skin pressure sensing) and energy utilization (such as ATP synthesis) are closely related to controllable ion transport within protein ion channels. By constructing biomimetic nanochannels and studying the ion transport behavior and mechanism in confined spaces, the ion gating properties, ion rectification properties, ion pumps, and other functions of protein ion channels can be achieved. Biomimetic intelligent energy devices and sensor devices based on ion transport can be constructed.
2. Construction of biomimetic ion based transistors and neurons
Neurons are the basic units for transmitting and storing intelligent life signals, and action potentials are the carriers of information and signals. The generation of action potentials is closely related to voltage responsive ion channels (also known as the "transistors" of life). By using biomimetic methods to construct ion based transistors with "ions as carriers", the existing "silicon+electron" transistor mode can be broken, achieving the generation of neuron like action potentials and the construction of ion circuits.
3. Biomimetic multi-scale ion based neural system
The implementation of multimodal computing and memory storage in intelligent life benefits from a vast neural network system. By constructing a neural network system based on ion transport, various brain like computing functions for synaptic signal transmission and information storage can be achieved, such as dual pulse facilitation, long-range enhancement/inhibition, memristive effect, etc. This lays a good foundation for the "intelligent life artificial intelligence" barrier free communication system, and ultimately has the potential to achieve biological neural electrophysiological regulation through biomimetic neural networks for the treatment of neurological diseases.